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Array Comp. Genomic Hybridization (aCGH)

aCGH dup20q

Why use aCGH to characterize your cell lines?

Array Comparative Genomic Hybridization (aCGH) is a high-resolution karyotype analysis alternative for the detection of unbalanced structural and numerical chromosomal aberrations with high-throughput capabilities. With the addition of Single Nucleotide Polymorphisms (SNPs), aCGH can also detect polylpoidy, loss of heterozygosity, and uniparental disomy.

Cell Line Genetics offers two different array comparative genomic hybridization arrays to help characterize your cell lines. Cell Line Genetics utilizes Agilent’s Microarray platform.

SurePrint G3 Human CGH Microarray Kit, 8x60K – High-throughput, low cost alternative to karyotyping. Average coverage every 41KB with increased coverage in Refseq genes (33KB)

SurePrint G3 Human Genome CGH+SNP Microarray Kit, 4x180K – High resolution array with SNPs included. Average coverage every 25KB with increased coverage in ISCA regions (5KB)

Sample Requirements download here.

Each sample must be accompanied by its own Test Requisition Form. Fill out a requisition form here.

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